Ahead of making use of ELIDEL Product, 1%, convey to your doctor about all of your current professional medical problems, such as should you:
It’s not known what result , if any, CYP3A inhibitors may have on Elidel degrees in The body. They might result in the drug to build up, which could improve your threat for side effects.*
ELIDEL® (pimecrolimus) Product, one% is contraindicated in persons using a heritage of hypersensitivity to pimecrolimus or any from the components from the product.
Topical pimecrolimus can also be useful for other problems as determined by your healthcare company.
Pimecrolimus was transferred across the placenta in oral rat and rabbit embryofetal developmental experiments.
Individuals who get ELIDEL Cream, one% and who acquire lymphadenopathy ought to have the etiology in their lymphadenopathy investigated. While in the absence of a transparent etiology to the lymphadenopathy, or from the presence of acute infectious mononucleosis, ELIDEL Product, 1% ought to be discontinued. Individuals who produce lymphadenopathy really should be monitored in order that the lymphadenopathy resolves.
Elidel is not intended for use as a protracted-time period treatment.* Your physician will help you ascertain the length of time you’ll use Elidel.
Based upon this facts plus the mechanism of action, You will find there's worry about a potential possibility with using topical calcineurin inhibitors, such as ELIDEL Cream, one%.
A battery of in vitro genotoxicity assessments, which includes Ames assay, mouse lymphoma L5178Y assay, and chromosome aberration exam in V79 Chinese hamster cells and an in vivo mouse micronucleus examination revealed no proof for your mutagenic or Kutyatáp clastogenic probable for your drug.
Following the administration of only one oral radiolabeled dose of pimecrolimus quite a few circulating Odemethylation metabolites had been noticed. Studies with human liver microsomes indicate that pimecrolimus is metabolized in vitro from the CYP3A sub-loved ones of metabolizing enzymes.
Pregnancy. It is not acknowledged if or how topical pimecrolimus could impact pregnancy or damage an unborn baby. Notify your Health care supplier When you are or program to be pregnant.
Elidel hasn't been encouraged for that treatment method of hyperpigmentation or acne. Hyperpigmentation (standard pores and skin discoloration) and acne are described as Uncomfortable side effects of Elidel.
Eczema can be a variety of pores and skin affliction. It takes place Whenever your immune procedure gets overactive and doesn’t work as standard.
Do not deal with the skin remaining treated with bandages, dressings or wraps. You can wear ordinary garments.